Newron in a nutshell
Newron (SIX: NWRN, XETRA: NP5) is a publicly listed biopharmaceutical company committed to improving the lives of patients with central and peripheral nervous system disorders.
Our lead compound, evenamide, is a first-in-class glutamate modulator currently in Phase III development. Evenamide has the potential to become the first add-on therapy for patients with treatment-resistant schizophrenia (TRS) and for poorly responding patients with chronic schizophrenia. Clinical data to date demonstrates significant and sustained improvements in key efficacy measures alongside a favourable safety profile – a rare combination amongst the currently available antipsychotic medications.
We have entered into development and commercialization agreements for evenamide with EA Pharma (a subsidiary of Eisai) for Japan and other Asian territories, as well as with Myung In Pharm for South Korea. Additional partnerships for other territories are currently being evaluated.
Newron has a proven track record in bringing CNS therapies to market. Our Parkinson’s disease treatment, Xadago® (safinamide), is approved in over 20 markets, including the USA, UK, EU, Switzerland, and Japan, and commercialized in partnerships with Zambon and Meiji Seika.
Strategy
Advancing evenamide – transforming schizophrenia treatment
Evenamide is our lead development asset and represents a potential breakthrough in the treatment of schizophrenia. Its differentiated mechanism of action (MoA) targets a significant unmet medical need in a large global market.
- Unique MoA: glutamate modulation through voltage-gated sodium channel blockade
- Add-on approach to enhance efficacy of existing antipsychotics
- Positive Phase II/III data and ongoing Phase III trials
Leveraging partnerships – enabling global reach
We aim to expand our network of strategic partners to support evenamide’s global development and commercialization. Recent collaborations in Asia provide a strong foundation for further development opportunities in other territories.
Expanding our pipeline through strategic in-licensing
In parallel, we are evaluating opportunities to in-license innovative CNS assets to strengthen and diversify our development portfolio.
Our People
Our History
ESG
We are committed to delivering innovative treatments to improve the quality of life for patients with CNS disorders. We do so by maximizing the market potential of our product Xadago, developing our compound Evenamide as add-on therapy for the treatment of positive symptoms of schizophrenia, and by partnering non-core assets and in-licensing strategically relevant assets.
While doing so, Newron's Board of Directors and Senior Management Team are committed to high standards of corporate governance, including transparency and accountability towards the company’s stakeholders. The corresponding Corporate Governance reporting is updated on a yearly basis and available in the most recent Annual Report here.
Newron has identified the following stakeholder groups to be of specific relevance for the company’s future success:
- Employees: Newron strives to offer an inspiring work environment. The well-being of our employees is key. Commitment is rewarded. It is the company’s ambition to act as motivating and attractive employer of choice within the global CNS community. Newron does not tolerate any form of harassment and treats all employees equally.
- Patients: It is our main purpose to improve the life of patients with CNS disorders. We do so by developing proprietary compounds as well as partnering and in-licensing assets. When conducting clinical trials, we carefully select the KOL and CRO that are responsible for planning and running the studies jointly with us and the involved authorities. We have the utmost respect for patients willing to participate in our clinical trials and avoid all issues (e.g. discrimination of specific populations) that might occur.
- R&D and Business partners: For Newron, sustainable collaborations with R&D and business partners is very important. Newron aims to act as reliable business partner, following and respecting the industry’s business ethics – and requires the same from its partners.
- Investors and financial community: Newron’s ambition is to create value for its shareholders in the long-term. Thus, Newron maintains a constant and trustful dialogue with shareholders, the financial community as well as the Swiss (SIX) and German (XETRA) stock exchanges where Newron’s shares are currently traded. Transparent communications is crucial. Risk management and business continuity play an important role in Newron’s corporate strategy.
- Society: Newron aims to be a Good Corporate Citizen, i.e. in the Milan (Italy) and New Jersey (USA) areas where the company currently has its offices. The same applies to locations where Newron is present within the framework of clinical trials. We pay attention to our ecological footprint and are working on further improving it.