Newron in a nutshell
Newron (SIX: NWRN, XETRA: NP5) is a publicly listed biopharmaceutical company committed to improving the lives of patients with central and peripheral nervous system disorders.
Our lead compound, evenamide, is a first-in-class glutamate modulator currently in Phase III development. Evenamide has the potential to become the first add-on therapy for patients with treatment-resistant schizophrenia (TRS) and for poorly responding patients with chronic schizophrenia. Clinical data to date demonstrates significant and sustained improvements in key efficacy measures alongside a favourable safety profile – a rare combination amongst the currently available antipsychotic medications.
We have entered into development and commercialization agreements for evenamide with EA Pharma (a subsidiary of Eisai) for Japan and other Asian territories, as well as with Myung In Pharm for South Korea. Additional partnerships for other territories are currently being evaluated.
Newron has a proven track record in bringing CNS therapies to market. Our Parkinson’s disease treatment, Xadago® (safinamide), is approved in over 20 markets, including the USA, UK, EU, Switzerland, and Japan, and commercialized in partnerships with Zambon and Meiji Seika.
Strategy
Advancing evenamide – transforming schizophrenia treatment
Evenamide is our lead development asset and represents a potential breakthrough in the treatment of schizophrenia. Its differentiated mechanism of action (MoA) targets a significant unmet medical need in a large global market.
- Unique MoA: glutamate modulation through voltage-gated sodium channel blockade
- Add-on approach to enhance efficacy of existing antipsychotics
- Positive Phase II/III data and ongoing Phase III trials
Leveraging partnerships – enabling global reach
We aim to expand our network of strategic partners to support evenamide’s global development and commercialization. Recent collaborations in Asia provide a strong foundation for further development opportunities in other territories.
Expanding our pipeline through strategic in-licensing
In parallel, we are evaluating opportunities to in-license innovative CNS assets to strengthen and diversify our development portfolio.